You might have any of the following symptoms if your cancer has spread to the lymph nodes: a lump or swelling under your armpit; swelling in your arm or hand (lymphoedema) a lump or swelling in your breast bone or collar bone area; One of the first places breast cancer can spread to is the lymph nodes under the arm on the same side as the breast . Metastatic breast cancer is breast cancer than has spread to another part of the body, such as the liver, bones, lungs, or brain. The symptoms of metastatic breast cancer can be very different depending on the location of the cancer. 8. How to manage the symptoms of secondary breast cancer in the bone Pain. Secondary breast cancer in the bone can cause pain in or near the affected area, though not all .